A novel histidine-histidine (His-His) photooxidative cross-link has been identified in an IgG4 antibody. It was formed between the side chain of a histidine residue of the antibody and histidine from the formulation buffer. The structure of the cross-link was elucidated using high performance liquid chromatography (HPLC) hyphenated to tandem mass spectrometry (MS/MS) with higher energy collisional dissociation (HCD). The cross-link was found in multiple conformations, as the location of the oxygen varied. Furthermore, the extent of cross-link formation was shown to correlate with the amount of light the antibody was exposed to as well as the solvent accessibility of each modification site.
 Human Plasma) Haptoglobin, (Phenotype 1-1) Human Plasma |
|
7536-1 |
Biovision |
|
EUR 321 |
 TAPI-1 |
|
B4686-1 |
ApexBio |
1 mg |
EUR 268 |
|
Description: TAPI-1 is an inhibitor of tumour necrosis factor with IC50 value of 8.09 ?M [1].TAPI-1 is an inhibitor of TACE/ADAM17 which catalyzes the cleavage of full-length APP to the soluble N-terminal fragment (sAPP?). |
 C14TKL-1 |
|
B5240-1 |
ApexBio |
1 mg |
EUR 399 |
 ?1-MSH |
|
B5427-1 |
ApexBio |
1 mg |
EUR 268 |
 CRSP-1 |
|
B5452-.1 |
ApexBio |
100 ug |
EUR 415 |
 ADWX 1 |
|
B5722-.1 |
ApexBio |
100 ug |
EUR 583 |
|
Description: ADWX 1 is a potent and selective inhibitor of KV1.3 channel with IC50 values of 1.89 pM and 0.65 nM for Kv1.3 and Kv1.1, respectively [1]. |
 Purotoxin 1 |
|
B5771-.1 |
ApexBio |
100 µg |
EUR 380 |
 Psalmotoxin 1 |
|
B5796-.1 |
ApexBio |
100 ug |
EUR 447 |
|
Description: IC50: 0.9 nMPsalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.Several ASIC subunits described: ASIC1a, ASIC1b, ASIC2a, ASIC2b, and ASIC3 with different kinetics, tissue distribution, and external pH sensitivities. |
 Rbin-1 |
|
B7823-1 |
ApexBio |
1 mg |
EUR 154 |
|
Description: Rbin-1 is an eukaryotic ribosome assembly inhibitor.All cellular proteins are synthesized by ribosomes, whose biogenesis is a complex multi-step process quickly completed in eukaryotes. |
 UK 1 |
|
C5006-1 |
ApexBio |
1 mg |
EUR 363 |
|
Description: UK 1, an unusual bis-benzoxazole metabolite isolated from Streptomyces sp. 517-02, is an inhibitor of topoisomerase II (Topo II) and hepatitis C viral replication. |
 KP372-1 |
|
C5053-1 |
ApexBio |
1 mg |
EUR 132 |
|
Description: IC50: 30-60 nM for thyroid cancer cells KP372-1 is a specific Akt inhibitor. The phosphatidylinositol 3' kinase (PI3K)/phosphatase, which is a key regulator of cell proliferation and survival, is mutated or activated in various cancers. |
 Flutax 1 |
|
B6986-1 |
ApexBio |
1 mg |
EUR 399 |
) Anti-HO-1 Monoclonal Antibody (HO-1-2) |
|
M00253-1 |
BosterBio |
1mg |
EUR 397 |
|
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat. |
 IL-1-beta Interleukin-1 betaHuman Recombinant Protein |
|
PROTP01584-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques. |
 MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein |
|
PROTP03956-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: MMP 1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus. |
 CDK7-IN-1 |
|
B4665-1 |
ApexBio |
1 mg |
EUR 358 |
 LPA2 antagonist 1 |
|
B4726-1 |
ApexBio |
1 mg |
EUR 319 |
 PACAP 1-27 |
|
B5075-1 |
ApexBio |
1 mg |
EUR 290 |
) Nociceptin (1-7) |
|
B5087-1 |
ApexBio |
1 mg |
EUR 399 |
) Hemokinin 1 (mouse) |
|
B5127-1 |
ApexBio |
1 mg |
EUR 321 |
) GIP (1-39) |
|
B5280-1 |
ApexBio |
1 mg |
EUR 609 |
 JMV 390-1 |
|
B5317-1 |
ApexBio |
1 mg |
EUR 242 |
) Hemokinin 1 (human) |
|
B5318-1 |
ApexBio |
1 mg |
EUR 340 |
 Echistatin, ?1 isoform |
|
B5391-.1 |
ApexBio |
100 ug |
EUR 583 |
 PACAP 1-38 |
|
B6625-1 |
ApexBio |
1 mg |
EUR 347 |
 SL 0101-1 |
|
B9008-1 |
ApexBio |
1 mg |
EUR 163 |
 Teicoplanin A3-1 |
|
C4943-1 |
ApexBio |
1 mg |
EUR 326 |
|
Description: Teicoplanin A3-1, also known as Antibiotic L 17054, is a glycopeptide antibiotic derived from Actinoplanes teichomyceticus and produces a potent broad spectrum antibiotic activity against gram-positive bacteria. |
 IDO-IN-1 |
|
C3211-1 |
ApexBio |
1 mg |
EUR 139 |
|
Description: IC50: 59 nMIDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor. |
) RN-1 (hydrochloride) |
|
C4247-1 |
ApexBio |
1 mg |
EUR 112 |
|
Description: RN-1 (hydrochloride) is a brain-penetrant, potent and irreversible LSD1 inhibitor with IC50 values of 10-70 nM [1]. Lysine-specific demethylase 1 (LSD1) is a flavin-dependent monoamine oxidase that demethylate mono- and di-methylated lysines, specifically histone 3, lysines 4 and 9. |
) StemRegenin 1 (hydrochloride) |
|
C3551-1 |
ApexBio |
1 mg |
EUR 118 |
|
Description: IC50: 127 nM in CD34+ cellsStemRegenin 1 is an aryl hydrocarbon receptor signaling antagonist.The aryl hydrocarbon receptor (AhR ) is a protein that is encoded by the AHR gene. |
 HPGDS inhibitor 1 |
|
B1046-1 |
ApexBio |
1 mg |
EUR 181 |
|
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation. |
 Sphingosine-1-phosphate |
|
B6707-1 |
ApexBio |
1 mg |
EUR 181 |
|
Description: Sphingosine-1-phosphate is an endogenous second messenger that involved in cell proliferation and survival and is a ligand for S1PR1 [1] [2]. |
 TASIN-1 hydrochloride |
|
B2088-1 |
Biovision |
|
EUR 142 |
 RAD51D (1-328 a.a.) Human Recombinant Protein) (1-328) RAD51D (1-328 a.a.) Human Recombinant Protein |
|
PROTO75771-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 XMIR-1 RNA oligo miRNA-1-3p with Xmotif |
|
XMIR-1 |
SBI |
10 rxn |
EUR 438 |
|
|
 Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 |
|
M04431-1 |
BosterBio |
100uL |
EUR 385 |
|
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human |
 TGF-b-1 Transforming Growth Factor-beta 1 Human protein |
|
PROTP01137-1 |
BosterBio |
Regular: 2.5ug |
EUR 1157 |
|
Description: Human Transforming Growth Factor-beta 1 purified from Human Platelets having a molecular mass of 25kDa.;The TGF-b 1 is purified by proprietary chromatographic techniques. |
) MCP-1 Monocyte Chemotactic Protein-1 Mouse Recombinant Protein (CCL2) |
|
PROTP10148-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: Monocyte Chemotactic Protein-1 Mouse Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 14 kDa. ;The MCP-1 is purified by proprietary chromatographic techniques. |
 Envelope-1, Dengue Virus Subtype 1 Recombinant Protein, Insect Cells |
|
PROTB1PNJ5-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: Recombinant Dengue Virus Subtype 1 produced in Insect Cells is a polypeptide chain containing amino acids 281-675 and having a molecular weight of approximately 50kDa. ;Dengue Envelope-1 is purified by proprietary chromatographic technique. |
 AssayMax ELISA Kit) Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit |
|
EI2200-1 |
AssayPro |
96 Well Plate |
EUR 477 |
 AssayMax ELISA Kit) Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit |
|
EI2301-1 |
AssayPro |
96 Well Plate |
EUR 477 |
 AssayMax ELISA Kit) Human KRAB-associated Protein 1 (KAP-1) AssayMax ELISA Kit |
|
EK2802-1 |
AssayPro |
96 Well Plate |
EUR 477 |
 AssayMax ELISA Kit) Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit |
|
EMI2200-1 |
AssayPro |
96 Well Plate |
EUR 477 |
 AssayMax ELISA Kit) Human Plasminogen Activator Inhibitor-1 (PAI-1) AssayMax ELISA Kit |
|
EP1100-1 |
AssayPro |
96 Well Plate |
EUR 417 |
) MCP-1 Monocyte Chemotactic Protein-1 Human Recombinant Protein (CCL2) |
|
PROTP13500-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: Monocyte Chemotactic Protein-1 Human Recombinant also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 76 amino acids and having a molecular mass of 8.6kDa. ;The MCP-1 is purified by proprietary chromatographic techniques. |
 GAD1 iso1 Glutamate Decarboxylase 1 Isoform-1 Human Recombinant Protein |
|
PROTQ99259-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: GAD1 iso1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 617 amino acids (1-594 a.a) and having a molecular mass of 69.3kDa. GAD1 iso1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif |
|
AXMIR-1 |
SBI |
10 reactions |
EUR 438 |
|
|
 Anti-PARP-1 Antibody |
|
A00122-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse. |
 Anti-Presenilin 1 Antibody |
|
A00138-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat. |
 Anti-CNG-1 Antibody |
|
A05494-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-Periphilin 1 Antibody |
|
A06996-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse. |
 Anti-Lyl-1 Antibody |
|
A07491-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
 Anti-GLI-1 Antibody |
|
A07972-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-Cerebellin 1 Antibody |
|
A09176-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-DOC-1 Antibody |
|
A09467-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse. |
 Anti-PAI-1 Antibody |
|
A00637-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat. |
 Anti-Flk-1 Antibody |
|
A00901-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse. |
 Anti-EDG-1 Antibody |
|
A01502-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat. |
 Anti-ROBO-1 Antibody |
|
A01530-1 |
BosterBio |
100ug |
EUR 455 |
|
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
 Bovine LIVER 1 EA* |
|
57123-1 |
Pel-Freez |
1 Each |
EUR 180.28 |
 Anti-NPDC-1 Antibody |
|
A12846-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-Bag-1 Antibody |
|
A02423-1 |
BosterBio |
50 ul |
EUR 397 |
|
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat. |
 Anti-TUB 1 Antibody |
|
A02917-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Dok-1 Antibody |
|
A03039-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat. |
 Anti-TFIIIB90-1 Antibody |
|
A03761-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse. |
 Anti-Atrophin-1 Antibody |
|
A03828-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat. |
 Supercoiled pHOT-1 DNA |
|
TG2030-1 |
TopoGen |
25 ug |
EUR 246 |
 Relaxed pHOT-1 DNA |
|
TG2035-1 |
TopoGen |
25 ug |
EUR 246 |
) Beta-Amyloid (1-11) |
|
A1002-1 |
ApexBio |
1 mg |
EUR 102 |
|
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein. |
) Amyloid ?-Protein (1-15) |
|
A1003-1 |
ApexBio |
1 mg |
EUR 113 |
|
Description: Beta-amyloid protein (A beta), a 39-43 amino acid peptide composed of a portion of the transmembrane domain and the extracellular domain of the amyloid precursor protein (APP), is also the principal component of amyloid. |
, rat) ANP (1-11), rat |
|
A1009-1 |
ApexBio |
1 mg |
EUR 84 |
|
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation. |
 alpha-1 antitrypsin fragment |
|
A1051-1 |
ApexBio |
1 mg |
EUR 108 |
|
Description: Alpha-1 antitrypsin (A1AT) (H2N-Leu-Gln-His-Leu-Glu-Asn-Glu-Leu-Thr-His-Asp-Ile-Ile-Thr-Lys-OH), which is known as serum trypsin inhibitor, is a protease inhibitor belonging to the serpin superfamily. |
, human) BNP (1-32), human |
|
A1105-1 |
ApexBio |
1 mg |
EUR 177 |
|
Description: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). |
 B-Raf IN 1 |
|
B4727-1 |
ApexBio |
1 mg |
EUR 118 |
NH2) Nociceptin (1-13)NH2 |
|
B5102-1 |
ApexBio |
1 mg |
EUR 184 |
) JIP-1 (153-163) |
|
B5130-1 |
ApexBio |
1 mg |
EUR 399 |
) Nogo-66 (1-40) |
|
B5247-1 |
ApexBio |
1 mg |
EUR 609 |
) Orphanin FQ (1-11) |
|
B5497-1 |
ApexBio |
1 mg |
EUR 226 |
 R-1 Methanandamide Phosphate |
|
C3352-1 |
ApexBio |
1 mg |
EUR 126 |
|
Description: R-1 Methanandamide Phosphate,a water soluble prodrug analog of AEA, exhibited similar activity to that of AEA in the growth inhibition of C6 glioma cells[1]. Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid (CB). |
